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Researchers show how to evaluate waning efficacy of COVID-19 vaccines


Researchers show how to evaluate waning efficacy of COVID-19 vaccines
Researchers in the United States have demonstrated how to estimate the potentially waning efficacy of vaccines designed to protect against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
The novel SARS-CoV-2 virus is the agent responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic that has now claimed the lives of more than 3 million people globally.
The team’s proposed methods address the challenges presented in assessing vaccine efficacy (VE) using blood or nasal samples that are only collected periodically during clinical trials where enrollment is staggered and crossover of placebo recipients to the vaccine arm occurs before the end of the study. ....

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