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Cureus | Alterations of Regional Homogeneity in Parkinson's Disease: A Resting-State Functional Magnetic Resonance Imaging (fMRI) Study

Objective

The objective of this study is to investigate the regional homogeneity (ReHo) of spontaneous brain activities in Parkinson’s disease (PD) patients.

Methods

In total, 20 PD patients and 20 matched normal controls (NCs) participants were recruited for this study. The regional homogeneity (ReHo) approach based on resting-state functional magnetic resonance imaging on a 3T MRI system was used to investigate local brain activity. We examined activity in two frequency bands, slow‐4 (0.027-0.073 Hz) and slow‐5 (0.010-0.027 Hz). Two-sample t-tests were used to determine the between-group differences in the ReHo data. Pearson correlation analysis was used to explore the relationships between the ReHo values and clinical indices in PD patients.

Results

Compared with NCs, PD patients showed decreased ReHo values in the right middle occipital gyrus, right cuneus, and left superior occipital gyrus, and increased ReHo values i ....

United States , New Zealand , Monte Carlo , Movement Disorder Society , Montreal Neurological Institute , Ge Healthcare , Unified Parkinson , Disease Rating Scale , Mini Mental State Examination , Data Processing Assistant , Neurological Institute , Decreased Reho ,

CBI recovers Rs 13 lakh during raid in Mumbai

The Central Bureau of Investigation (CBI) on Wednesday said it has recovered cash of Rs 13.40 lakh during searches in connection with a case related to allegations of fraudulent settlement of EPF claims into bogus accounts.Searches were . ....

New Delhi , Regional Office , Head Office , Provident Fund Commissioners , Central Bureau Of Investigation , Central Bureau , Senior Social Security Assistant , Social Security Assistant , Data Processing Assistant , Assistant Provident Fund Commissioners , Accounts Officer , Section Supervisor , Social Security ,