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The stimulation of deep brain structures has thus far only been possible with invasive methods. Transcranial electrical temporal interference stimulation (tTIS) is a novel, noninvasive technology that might overcome this limitation. The initial proof-of-concept was obtained through modeling, physics experiments and rodent models. Here we show successful noninvasive neuromodulation of the striatum via tTIS in humans using computational modeling, functional magnetic resonance imaging studies and behavioral evaluations. Theta-burst patterned striatal tTIS increased activity in the striatum and as...

Exploring whether the aberrant cortical morphology was associated with insomnia in generalized anxiety disorder

The Mediterranean diet (MedDiet) has been associated with cognitive performance. Yet, controlled trials have yielded contradictory results. To tackle this controversy, a comprehensive multimodal analysis of the association of the MedDiet with cognitive performance and brain structure in normative aging is still necessary. To address this issue, community-dwellers ≥50 years from a cohort study on normative aging (n=76) underwent a i) magnetic resonance imaging session with two acquisitions: structural and Diffusion-Weighted Imaging; ii) neuropsychological battery of tests focusing on memory a...

Objective:New antidepressant treatments are needed that are effective, rapid acting, safe, and tolerable. Intermittent theta-burst stimulation (iTBS) is a noninvasive brain stimulation treatment th...

OriginLab Releases New Data Analysis and Graphing Software, Origin 2021b Latest version includes Enhancements to Embedded Python Support, GUI Tools for NetCDF Climate Data, Mini Toolbars for 3D Graphs, Improvements to Worksheet Calculations, New Graph Types and Apps. News provided by Share this article Share this article NORTHAMPTON, Mass., May 4, 2021 /PRNewswire/ -- OriginLab, a leading publisher of data analysis and graphing software, today announced the release of Origin® and OriginPro®  2021b. This latest version of OriginLab's award-winning software application adds over 100 new feat...