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Transgene Expands Phase II Clinical Trial of Therapeutic Vaccine TG4001 in Combination With Avelumab Versus Avelumab Monotherapy in Patients With HPV16-positive Anogenital Cancers


Transgene Expands Phase II Clinical Trial of Therapeutic Vaccine TG4001 in Combination With Avelumab Versus Avelumab Monotherapy in Patients With HPV16-positive Anogenital Cancers
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Trial will focus on patients without liver metastases, based on encouraging data in Phase Ib/II study
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Trial targets indications where clinical outcomes can be improved versus standard therapeutic options and immune checkpoint inhibitors ( ICIs )
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Continued clinical collaboration with Merck KGaA, Darmstadt, Germany, and Pfizer to conduct the expanded Phase II study
Regulatory News:
Transgene (Paris:TNG) (Euronext Paris: TNG), a biotech company that designs and develops virus-based immunotherapeutics against cancer, today announces the expansion of a randomized, controlled study with TG4001 in combination with avelumab versus avelumab monotherapy in patients with HPV16-positive anogenital tumors (NCT: 03260023) ....

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A Trippy Visualization Charts the Internet's Growth Since 1997


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In November 2003, security researcher Barrett Lyon was finishing college at California State University, Sacramento, while working full time as a penetration tester a hacker companies hire to find weaknesses in their own digital systems. At the beginning of each job, Lyon would do some basic reconnaissance of the customer s infrastructure: “case the joint,” as he puts it. He realized he was essentially refining and repeating a formula to map what the new target network looked like. “That formula ended up being an easy piece of software to write, so I just started having this software do all the work for me,” Lyon says. ....

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CNN CNN Newsroom July 13, 2014 19:21:15

Transcripts for CNN CNN Newsroom 20140713 19:21:15
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