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Exelixis (EXEL) Announces More Detailed Results of Phase 3 COSMIC-313 Trial in Advanced Kidney Cancer at ESMO

Exelixis (EXEL) Announces More Detailed Results of Phase 3 COSMIC-313 Trial in Advanced Kidney Cancer at ESMO
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Exelixis Announces Detailed Results from Phase 3 COSMIC-313 Pivotal Trial in Patients with Previousl

– Cabozantinib in combination with nivolumab and ipilimumab significantly reduced the risk of disease progression or death compared with the combination of nivolumab and ipilimumab –– Median progression-free survival was not yet reached with the combination of cabozantinib, nivolumab and ipilimumab versus 11.3 month. ....

United States , Toni Choueiri , Susan Hubbard , Vickil Goodman , Lindsay Treadway , Nancy Kohlberg , International Metastatic , Daiichi Sankyo Company , European Society Of Medical Oncology , Takeda Pharmaceutical Company , Database Consortium , Exelixis Inc , Public Affairs , European Union , Product Development Medical Affairs , Dana Farber Cancer Institute , Radiology Committee , Bristol Myers Squibb , American Cancer Society , Genentech Inc , Professor Of Medicine At Harvard Medical School , Lank Center , Exchange Commission , Presidential Symposium , Medical Oncology , Genitourinary Oncology ,

Three-drug combination slows progression of advanced kidney cancer

Patients treated with the three-drug combination had a 27% lower risk of progression or death compared to those on the two immunotherapy drugs. ....

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Triplet therapy slows progression of advanced kidney cancer

A targeted kinase inhibitor added to a two-drug immunotherapy combination slowed the progression of advanced kidney cancer in previously untreated patients, according to research led by an oncologist from Dana-Farber Cancer Institute. ....

France General , Toni Choueiri , Emily Henderson , Lank Center , International Metastatic , European Society Of Medical Oncology , Dana Farber Cancer Institute , Database Consortium , Dana Farber Cancer , Genitourinary Cancer , European Society , Medical Oncology , Presidential Symposium , Kidney Cancer , Clinical Trial , Kinase Inhibitor , Renal Cell Carcinoma ,

Exelixis Announces Detailed Results from Phase 3 COSMIC-313 Pivotal Trial in Patients with Previously Untreated Advanced Kidney Cancer at ESMO 2022

08.09.2022 - Exelixis, Inc. (Nasdaq: EXEL) today announced detailed results from COSMIC-313, an ongoing phase 3 pivotal trial evaluating the combination of cabozantinib (CABOMETYX), nivolumab and ipilimumab versus the combination of nivolumab and ipilimumab in . ....

United States , Vickil Goodman , International Metastatic , Daiichi Sankyo Company , Genentech Inc , Takeda Pharmaceutical Company , Database Consortium , Exchange Commission , Exelixis Inc , European Union , Product Development Medical Affairs , Radiology Committee , Bristol Myers Squibb , American Cancer Society , Response Evaluation Criteria , Solid Tumors , Blinded Independent Radiology Committee , Executive Vice President , Product Development , Medical Affairs , Chief Medical Officer , Ipsen Pharma , Takeda Pharmaceutical Company Limited , Hypertensive Crisis , Plantar Erythrodysesthesia , Impaired Wound Healing ,