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Durable Antitumor Activity in ccRCC With Combination Belzutifan/Cabozantinib

“Belzutifan plus cabozantinib continue to show durable anti-tumor activity in patients with clear cell RCC who are treatment naïve or previously treated,” said Toni K. Choueiri, MD. ....

United States , Dana Farber Cancer Institute , France General , Nat Genet , Tonik Choueiri , Genitourinary Oncology Disease Center , European Society For Medical Oncology , Harvard Medical School , Lank Center , European Society Of Medical Oncology , International Metastatic , Database Consortium , Medical Oncology , Annual Congress , Genitourinary Oncology , European Society , Esmo 2023 , Clear Cell Rcc , Clear Cell Renal Carcinoma , Kidney Cancer ,

Belzutifan Plus Cabozantinib Delivers Durable Responses in ccRCC

Belzultifan in combination with cabozantinib generated durable responses independent of International Metastatic RCC Database Consortium risk category in patients with treatment-naïve clear cell renal cell carcinoma or those who had received prior immunotherapy. ....

United States , France General , Dana Farber Cancer Institute , Nat Genet , Belzultifan Welireg , Tonik Choueiri , Genitourinary Oncology Disease Center , Harvard Medical School , European Society Of Medical Oncology , International Metastatic , Database Consortium , Lank Center , Genitourinary Oncology , European Society , Medical Oncology , Belzultifan In Combination With Cabozantinib , Clear Cell Renal Carcinoma , Litespark 003 Trial ,

SAMETA Trial Evaluates Efficacy of Savolitinib Plus Durvalumab in MET-Driven Papillary RCC

The safety and efficacy achieved with the combination of savolitinib and durvalumab vs standard-of-care sunitinib or durvalumab monotherapy will be evaluated in patients with MET-driven papillary renal cell carcinoma in the phase 3 SAMETA trial. ....

United States , Dana Farber Cancer Institute , Bristol Myers Squibb , Roche Genentech , Calithera Biosciences , Tonik Choueiri , Platformq Health , Pharma Group , Corvus Pharmaceuticals , Life Sciences , Kidney Cancer Association , Alexion Pharmaceuticals , Analysis Group , Database Consortium , Gilead Sciences , Navinata Health , Sanofi Aventis , Health Interactions , Fishawack Group Of Companies , Infinity Pharmaceuticals , Kidney Cancer Research Summit , Foundation Medicine , International Metastatic , Precede Bio , Tempest Therapeutics , Arcus Biosciences ,

New Tool Promises Improved Patient Selection for Cytoreductive Nephrectomy

A new screening tool could improve patient selection for cytoreductive nephrectomy in metastatic renal cell carcinoma (mRCC). ....

United States , University Medical Center , Rush University , Gary Steinberg , E Jason Abel , Riccardo Autorino , Rohith Arcot , University Of Texas Md Anderson Cancer Center , University Of Wisconsin , Public Health In Madison , Emory University In Atlanta , Moffitt Cancer Center , Penn State Miltons Hershey Medical Center , Database Consortium , International Metastatic , Ochsner Md Anderson Cancer Center , University Of Wisconsin School Medicine , Surgical Innovation Clinical Research , Wisconsin School , Public Health , Cytoreductive Nephrectomy Score , Emory University , Penn State Milton , Medical Center , Cancer Center , European Urology ,

Stereotactic Radiation Strategies May Bolster RCC Multi-Modality Management Efforts

Raquibul Hannan, MD, PhD, discusses the benefits of using stereotactic radiation in patients with localized RCC who are unfit for surgery, research findings indicating improved outcomes in patients who received radiation for metastatic disease, and how this radiation technique may work in concert with systemic therapy. ....

United States , Raquibul Hannan , Ut Southwestern Medical Center , International Metastatic , Database Consortium , Kidney Cancer Research Summit , Genitourinary Radiation Oncology Service , Cancer Research Summit , Radiation Oncology , Medical Center ,