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Machine-learning algorithm uses structure pre

DeepMind is releasing AlphaMissense, a tool researchers can use to learn more about the effects that missense mutations – which make up the majority of “variants of uncertain significance” – have on disease. AlphaMissense could help identify pathogenic missense mutations and previously unknown disease-causing genes. Uncovering the root causes of disease is one of the greatest challenges in human genetics. Many of the genetic mutations that cause disease in humans occur in protein-coding regions. Although the capacity to sequence DNA and identify disease-causing variants has substantially increased, the ability to interpret their effects remains limited. This problem is particularly acute for missense variants, genetic mutations that alter the amino acid sequence of proteins. The average person carries thousands of missense variants, most of which are benign, but others of which are pathogenic. Very few missense variants have been confirmed by experts, so their pathogenic versus ....

Jun Cheng , Deepmind Alphafold , Saraha Teichmann ,

What do Nobel prizewinners think of ChatGPT? | Times Higher Education (THE)

Nobel-winning scientists are now using large language models, but experts say their impact on research is only just starting ....

United States , Martin Chalfie , Michael Levitt , Sergey Brin , Albert Einstein , Deepmind Alphafold , Shwetak Patel , Avram Hershko , Columbia University , Stanford University , University Of Washington , Technion Israel Institute Of Technology , South Africa Born , Nobel Prize , Professor Levitt , Professor Chalfie , Lindau Nobel Laureates Meeting , Professor Hershko , Technion Israel Institute , Turing Award , Professor Patel , American Economic Review , Ideas Harder ,

Unfolding AlphaFold: The 'protein-folding problem' and its solution

The prediction of a protein structure from its sequence will be an incredible tool. ....

City Of , United Kingdom , Demis Hassabis , Mohammed Alquraishi , Shane Legg , Deepmind Alphafold , Venki Ramakrishnan , Christianb Anfinsen , Royal Society , European Molecular Biology Laboratory Bioinformatics Institute , Columbia University , Critical Assessment , Protein Structure Prediction , Global Distance Test , Nobel Laureate , John Moult , Alpha Zero , European Molecular Biology Laboratory , European Bioinformatics , Protein Folding , Protein Folding Solutions , Hiv Virus , Dna Testing ,

AI's multi-view wave is coming, and it will be powerful

The rise of multiple modalities of data will be united in a multi-sided view of the world, which could be an important step toward programs that perform "reasoning" and "planning". ....

Tiernan Ray , Deepmind Alphafold , Yann Lecun , Ravid Shwartz Ziv , York University , Meta Properties , Information Fusion , New York University , Stable Diffusion ,

AI-discovered drugs will be for sale soon

It takes forever to get drugs on the market. AI could help speed up the process. ....

United States , Henry Ford , Swarat Chaudhuri , Bowen Lou , Regina Barzilay , Alex Zhavoronkov , Google Bard , Deepmind Alphafold , Chris Gibson , Ford Motor Company , Stanford University , Massachusetts Institute Of Technology , School Of Engineering , University Of Texas Austin , University Of Connecticut School Business , Space Odyssey , Massachusetts Institute , Hong Kong Based , Big Pharma , Texas Austin , Enamine Real , Insilico Medicine ,