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Apr 15 2021 Read 7 Times A new international study(1) has provided a template for how to develop directly-acting antivirals with novel modes of action, that would combat COVID-19 by suppressing the SARS-CoV-2 viral infection. The study focused on the macrodomain part of the Nsp3 gene product that SARS-CoV-2 uses to suppress the host cell’s natural antiviral response. This part of the virus’s machinery, also known as Mac1, is essential for its reproduction: previous studies have shown that viruses that lack it cannot replicate in human cells, suggesting that blocking it with a drug would h...

07 April 2021 Imperial, Shell and Diamond Light Source are launching an EPSRC-funded Programme on materials and processes for the energy transition. The EPSRC Prosperity Partnership, known as InFUSE, will examine how technologies like batteries, electric vehicles, chemical production, and carbon capture and storage (CCS) can be improved by understanding interfaces in these systems, enhancing sustainability and enabling a transition to a green economy. Transitioning to renewable, sustainable energy needs us all to think a little differently. Professor Mary Ryan The partnership will involv...

Credit: University of Southampton New research has for the first time compared images of the protein spikes that develop on the surface of cells exposed to the Oxford-AstraZeneca vaccine to the protein spike of the SARS-CoV-19 coronavirus. The images show that the spikes are highly similar to those of the virus and support the modified adenovirus used in the vaccine as a leading platform to combat COVID-19. The SARS-CoV-2 virus, which causes COVID-19, has a large number of spikes sticking out of its surface that it uses to attach to, and enter, cells in the human body. These spikes are coated...

Unilever and Lubrizol green R&D projects snap up share of £75m UK funding Content by subject If you already have an account please use the link below to sign in. If you have any problems with your access or would like to request an individual access account please contact our customer service team. Unilever's Materials Innovation Factory in Liverpool | Credit: Unilever Winners of £75m public-private funding round for innovative technologies announced as government faces flak for 'effective cut' to UK's research budget post-Brexit Projects exploring how shampoo, soap and other household good...

Researchers used high-resolution imaging to see dental tissues in the skull of a 3.67-million-old skull of a prehuman ancestor.