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New research addresses a gap in understanding how ketamine's impact on individual neurons leads to pervasive and profound changes in brain network function.
A World Health Organization Essential Medicine, ketamine is widely used at varying doses for sedation, pain control, general anesthesia and as a therapy for treatment-resistant depression.
If anesthesiologists had a rigorous means to manage dosing, they could deliver less medicine, maintaining exactly the right depth of unconsciousness while reducing postoperative cognitive side effects in vulnerable groups like the elderly. But with m
A new closed-loop system based on brain state monitoring accurately controls unconsciousness by automating doses of the anesthetic drug propofol every 20 seconds.
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