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Norwegian explorer Jannicke Mikkelsen said she has been left unable to sleep as rescuers scour the remote Atlantic to find her friend Hamish Harding and four others.
Leaders in the submersible industry sent a letter to OceanGate CEO Stockton Rush - who is currently missing along with the vessel - urging him to take caution.
The Titan submersible has been missing since 9.45am on Sunday morning after being launched into the Atlantic at 8am.
Mike Reiss, who was a producer on The Simpsons, revealed that he is 'not optimistic' about the rescue of the five passengers on the sub, which has been missing since 9.45am on Sunday.
A team from France and a US Navy ship are expected to arrive in Canada on Wednesday to operate a remotely operated robot and a submarine, which are deployed from the ship.