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Parasites which cause malaria may have adapted to overcome the protection offered by the sickle haemoglobin gene mutation, according to a study published in Nature.
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Genome variation data on more than 7,000 malaria parasites from 28 endemic countries is released today (24 February) in
Wellcome Open Research. It has been produced by MalariaGEN, a data-sharing network of groups around the world who are working together to build high-quality data resources for malaria research and disease control.
This open data release represents the world s largest resource of genomic data on malaria parasite evolution and drug resistance. It provides benchmark data on parasite genome variation that is needed in the search for new drugs and vaccines, and in the development of surveillance tools for malaria control and elimination.
Malaria is a major global health problem causing an estimated 409,000 deaths in 2019, with 67 per cent of deaths occurring in children under five years of age . This data resource focuses on Plasmodium falciparum, the species of malaria parasite that is responsible for the most common and deadliest form of the disease.