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A gene called  GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania. Developmental Cell, discovered that the protein encoded by  GAS2 is crucial for maintaining the structural stiffness of support cells in the inner ear that normally help amplify incoming sound waves. They showed that inner ear support cells lacking functional  GAS2 lose their amplifier abilities, causing severe hearing impairment in mice. The researchers also identified people who...

Discovery of a new genetic cause of hearing loss illuminates how inner ear works A Penn Medicine study shows a link between mutations of the GAS2 gene and the ability to amplify incoming sound, providing a research target for future gene therapy. A gene called  GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in Penn’s Perelman School of Medicine. Developmental Cell, discovered that the protein encoded by  GAS2 is crucial for maintaining the structural stiffness of support cells in the ...

Researchers Pinpoint New Genetic Mutation Linked to Hearing Loss Source: © robodread - Fotolia.com May 10, 2021 According to the CDC, 50–60% of hearing loss in babies is due to genetic causes. However, there are also a number of things in the environment that can cause hearing loss. In some cases, hearing loss is caused when both genes and the environment work together. A new mouse study by researchers at the Perelman School of Medicine at the University of Pennsylvania demonstrated that a gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss. Dev...

A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania.

PHILADELPHIA-- A gene called GAS2 plays a key role in normal hearing, and its absence causes severe hearing loss, according to a study led by researchers in the Perelman School of Medicine at the University of Pennsylvania. Developmental Cell, discovered that the protein encoded by GAS2 is crucial for maintaining the structural stiffness of support cells in the inner ear that normally help amplify incoming sound waves. They showed that inner ear support cells lacking functional GAS2 lose their amplifier abilities, causing severe hearing impairment in mice. The researchers also identified p...