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A former Casper doctor and his brother who distributed millions of opioids and other drugs and laundered the proceeds lost the appeal of his conviction and sentence last week. The Denver-based 10th U.S. Circuit Court of Appeals upheld the verdict and 25-year sentence of Dr. Shakeel Kahn, who was convicted after a 20-day trial in May 2019 of a massive prescription drug conspiracy resulting in death, a firearms count, other drug conspiracy counts, and running a continuing criminal enterprise. Shakeel’s brother, Nabeel Khan, was convicted of the drug conspiracy resulting in death and a firearms count. The brothers had filed joint appeals, and the three appellate judges combined their appeals into one ruling.