New Cancer Treatment 2.5x More Effective in Tumors with DNA Mutations
Discover how the cancer drug- nivolumab is 2.5 times more responsive against tumors with mitochondrial DNA mutations.
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Discover how the cancer drug- nivolumab is 2.5 times more responsive against tumors with mitochondrial DNA mutations.
For the first time, mitochondrial DNA mutations could be used with immunotherapy to increase the chances of successful treatments.
Some cancers are treated with immunotherapy - drugs that harness the body's natural defences to attack cancer cells - but with varying degrees of success.
<ul> <li><strong>Cancer Research UK-funded scientists at the Cancer Research UK Scotland Institute discover that tumours with high levels of mitochondrial DNA mutations are two and a half times more likely to respond to treatment. </strong></li> <li><strong>Link between mitochondria – which generates energy for cancer – and response to treatment shown for the first time. </strong></li> <li><strong>Discovery opens up possibility for tests to identify patients with defective mitochondria an...
Cancer Research UK-funded scientists have made an unusual discovery that could help to identify patients who are up to two and a half times more likely to respond to currently available cancer drugs.