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The intravenous delivery of immune-modulating cells may someday slow the expansion of bulges in the aorta, known as abdominal aortic aneurysms.
Abdominal aortic aneurysm, a weakening and ballooning of the aorta, the largest blood vessel in the body, may result in a life-threatening rupture. In a small, preliminary study examining a potential treatment to keep small abdominal aortic aneurysms from growing to a dangerous size, intravenous administration of immune-modulating cells resulted in a significant decrease in pro-inflammatory cells, and with higher doses, there was a decrease in aneurysm size.