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COVID-19 infection may promote aortic aneurysms and new treatment may slow its growth

The intravenous delivery of immune-modulating cells may someday slow the expansion of bulges in the aorta, known as abdominal aortic aneurysms. ....

United States , Stanford University , Kristin Wancyzk , Michael Ingram , Jia Guo , Toru Ikezoe , Ravi Mylvaganan , Raghu Motaganahalli , Michaelp Murphy , Elsar Chidester , Baohui Xu , Ashley Gutwein , Mithun Sinha , Sihai Zhao , Humraazs Samra , Katherin Leckie , Anush Motaganahalli , Ronaldl Dalman , Makoto Samura , Emily Henderson , Paul Terito , American Heart Association , Indiana University School Of Medicine , American Heart Association Vascular Discovery , Veterans Administration , Cryptic Masons Medical Research Foundation ,

New Treatment May Shrink Abdominal Aortic Aneurysm, COVID May Speed Growth

New Treatment May Shrink Abdominal Aortic Aneurysm, COVID May Speed Growth
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United States , Stanford University , Makoto Samura , Mithun Sinha , Raghu Motaganahalli , Ravi Mylvaganan , Kristin Wancyzk , Michael Ingram , Jia Guo , Elsar Chidester , Toru Ikezoe , Ashley Gutwein , Katherin Leckie , Baohui Xu , Ronaldl Dalman , Humraazs Samra , Anush Motaganahalli , Sihai Zhao , Paul Terito , Michaelp Murphy , American Heart Association Vascular Discovery , Stanford University School Of Medicine , American Heart Association , Stanford Research Repository Database , Indiana University School Of Medicine , Cryptic Masons Medical Research Foundation ,

Abdominal aortic aneurysm: new treatment may

Abdominal aortic aneurysm, a weakening and ballooning of the aorta, the largest blood vessel in the body, may result in a life-threatening rupture.
In a small, preliminary study examining a potential treatment to keep small abdominal aortic aneurysms from growing to a dangerous size, intravenous administration of immune-modulating cells resulted in a significant decrease in pro-inflammatory cells, and with higher doses, there was a decrease in aneurysm size. ....

United States , Stanford University , Jia Guo , Makoto Samura , Michael Ingram , Ravi Mylvaganan , Ronaldl Dalman , Paul Terito , Humraazs Samra , Kristin Wancyzk , Baohui Xu , Elsar Chidester , Michaelp Murphy , Mithun Sinha , Ashley Gutwein , Raghu Motaganahalli , Toru Ikezoe , Katherin Leckie , Anush Motaganahalli , Sihai Zhao , Indiana University School Of Medicine , Stanford Research Repository Database , American Heart Association , Cryptic Masons Medical Research Foundation , Council On Genomic , Veterans Administration ,

Immune-modulating cells may slow small AAA progression; COVID-19 may quicken it

IV allogeneic mesenchymal stromal cells may reduce inflammatory response and thereby reduce the progression of small abdominal aortic aneurysms, a speaker reported.A second study presented at the American Heart Association’s Vascular Discovery: From Genes to Medicine Scientific Sessions demonstrated that SARS-CoV-2 infection — in addition to other risk factors — could cause ....

United States , Richard Smith , Baohui Xu , Byscott Buzby , Humraazs Samra , Stanford University School Of Medicine , Indiana University School Of Medicine , American Heart Association Vascular Discovery , American Heart Association , Vascular Discovery , From Genes , Medicine Scientific Sessions , Indiana University School , Stanford University School , Published May ,