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Study reveals new approach for engineering stable articular cartilage

A new study assesses the effect of the gremlin-1 (GREM1) protein on the in vitro and in vivo stability of bone marrow stem cell (BMSC)-derived cartilage engineered within scaffolds. ....

Daniel Kelly , Johnp Fisher , Emily Henderson , Tissue Engineering Co , University Of Maryland , Trinity College , Trinity College Dublin Ireland , Fischell Family Distinguished Professor Department , Tissue Engineering , Trinity College Dublin , Tissue Engineering Co Editor In Chief , Fischell Family Distinguished Professor , Department Chair , Engineering Complex Tissues , Bone Marrow , Cellular Biology , Genetic Engineering , N Vitro , N Vivo , Material Science , Tissue Engineering ,

Dual release microparticle system promotes cranial bone defect healing

A new dual delivery system designed to sequentially release BMP2 and IGF1 in microparticles in an injectable hydrogel successfully healed an 8-mm cranial defect in rats. ....

Johnp Fisher , Yunzhi Peter Yang , Emily Henderson , Tissue Engineering Co , University Of Maryland , Stanford University School Of Medicine , Fischell Family Distinguished Professor Department , Tissue Engineering , Stanford University School , Tissue Engineering Co Editor In Chief John , Fischell Family Distinguished Professor , Department Chair , Engineering Complex Tissues , Cellular Biology , Genetic Engineering , Material Science , Tissue Engineering ,

Solid bone marrow aspirates may be a promising therapeutic approach for promoting wound healing

A new study compares the regenerative potential of blood/bone marrow aspirate concentrates obtained from arterial blood, venous blood, and bone marrow aspirate. The study, conducted in rabbits, is reported in the peer-reviewed journal Tissue Engineering Part A. ....

Masako Fujioka Kobayashi , Johnp Fisher , Emily Henderson , Tissue Engineering Co , University Of Maryland , Nippon Dental University , Fischell Family Distinguished Professor Department , Tissue Engineering Part , Tissue Engineering Co Editor In Chief , Fischell Family Distinguished Professor , Department Chair , Engineering Complex Tissues , Bone Marrow , Cellular Biology , Genetic Engineering , Material Science , Plastic Surgery , Tissue Engineering , Wound Healing ,

Regenerative Potential of Solid Bone Marrow Aspirate Concentrate

Regenerative Potential of Solid Bone Marrow Aspirate Concentrate
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Masako Fujioka Kobayashi , Johnp Fisher , Tissue Engineering Co , University Of Maryland , Mary Ann Liebert Inc , Nippon Dental University , Fischell Family Distinguished Professor Department , Tissue Engineering , Tissue Engineering Co Editor In Chief John , Fischell Family Distinguished Professor , Department Chair , Engineering Complex Tissues , Ann Liebert , Genetic Engineering , Biotechnology News , Mary Ann Liebert ,

Gelatin hydrogel can be used in trophoblast spheroid motility assays, shows study

Gelatin hydrogel can be used in trophoblast spheroid motility assays, shows study
Trophoblast cells, which surround the developing blastocyst in early pregnancy, play an important role in implantation in the uterine wall. A new multidimensional model of trophoblast motility that utilizes a functionalized hydrogel is described in the peer-reviewed journal
Tissue Engineering, Part A.
This valuable new tool, based on a methacrylamide-functionalized gelatin hydrogel, can be used for three-dimensional trophoblast spheroid motility assays. It can resolve quantifiable differences in outgrowth area and viability in the presence of a known invasion promoter and a known invasion inhibitor.
Implantation involves a highly coordinated molecular dialogue between endometrial cells and trophoblast cells. Developing a deeper understanding of the biological mechanisms surrounding implantation may provide critical insights into pregnancy and pregnancy disorders. ....

United States , University Of Illinois , Brendan Harley , Johnp Fisher , Emily Henderson , Tissue Engineering Co , University Of Maryland , Fischell Family Distinguished Professor Department , Tissue Engineering , Tissue Engineering Co Editor In Chief John , Fischell Family Distinguished Professor , Department Chair , Engineering Complex Tissues , ஒன்றுபட்டது மாநிலங்களில் , பல்கலைக்கழகம் ஆஃப் இல்லினாய்ஸ் , பிரெண்டன் ஹார்லி , எமிலி ஹென்டர்சன் , திசு பொறியியல் இணை , பல்கலைக்கழகம் ஆஃப் மேரிலாந்து , திசு பொறியியல் , திசு பொறியியல் இணை ஆசிரியர் இல் தலைமை ஜான் , துறை நாற்காலி , பொறியியல் சிக்கலான திசுக்கள் ,