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Dual release microparticle system promotes cranial bone defect healing

A new dual delivery system designed to sequentially release BMP2 and IGF1 in microparticles in an injectable hydrogel successfully healed an 8-mm cranial defect in rats. ....

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Regenerative Potential of Solid Bone Marrow Aspirate Concentrate

Regenerative Potential of Solid Bone Marrow Aspirate Concentrate
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Gelatin hydrogel can be used in trophoblast spheroid motility assays, shows study

Gelatin hydrogel can be used in trophoblast spheroid motility assays, shows study
Trophoblast cells, which surround the developing blastocyst in early pregnancy, play an important role in implantation in the uterine wall. A new multidimensional model of trophoblast motility that utilizes a functionalized hydrogel is described in the peer-reviewed journal
Tissue Engineering, Part A.
This valuable new tool, based on a methacrylamide-functionalized gelatin hydrogel, can be used for three-dimensional trophoblast spheroid motility assays. It can resolve quantifiable differences in outgrowth area and viability in the presence of a known invasion promoter and a known invasion inhibitor.
Implantation involves a highly coordinated molecular dialogue between endometrial cells and trophoblast cells. Developing a deeper understanding of the biological mechanisms surrounding implantation may provide critical insights into pregnancy and pregnancy disorders. ....

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Trophoblast motility in a gelatin hydrogel

Trophoblast motility in a gelatin hydrogel
New Rochelle, NY, December 18, 2020 Trophoblast cells, which surround the developing blastocyst in early pregnancy, play an important role in implantation in the uterine wall. A new multidimensional model of trophoblast motility that utilizes a functionalized hydrogel is described in the peer-reviewed journal
Tissue Engineering, Part A. Click here to read the full-text article free on the
Tissue Engineering website through January 18, 2020.
This valuable new tool, based on a methacrylamide-functionalized gelatin hydrogel, can be used for three-dimensional trophoblast spheroid motility assays. It can resolve quantifiable differences in outgrowth area and viability in the presence of a known invasion promoter and a known invasion inhibitor. ....

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