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Association of genetically proxied PDE5 inhibition with measures of fertility, sexual behaviour, and wellbeing

Researchers performed a two-sample Mendelian randomization analysis to investigate the associations between genetically proxied suppression of PDE5, a recognized pharmacological target for erectile dysfunction, fertility, subjective wellness, and sexual behavior. ....

United Kingdom , International Consortium For Blood Pressure , International Consortium , Blood Pressure , United Kingdom Biobank , Elsworth United Kingdom Biobank , Blood Pressure , Erectile Dysfunction , Pulmonary Hypertension ,

UB research identifies key mechanism in infantile cystinosis

University at Buffalo research has identified how a misstep in the genesis of a key component of the kidney causes infantile cystinosis, a rare disease that significantly shortens the lifespan of patients. ....

Ramkumar Thiyagarajan , Maryl Taub , Jacobs School Of Medicine , University At Buffalo , Cystinosis Research Foundation , Biomedical Sciences , International Journal Of Molecular Sciences , University Of Kansas , International Journal , Molecular Sciences , Jacobs School , Cystinosis Research , Induced Pluripotent Stem Cells , Rare Disease , Stem Cells ,

New SARS-CoV-2 variant JN.1 shows increased transmissibility and immune resistance

A Japanese study published in BioRxiv explores the virological characteristics of the SARS-CoV-2 JN.1 variant, finding it has a higher effective reproductive number and stronger resistance to immunity from other variants, potentially due to the L455S spike protein mutation. ....

United Kingdom , United States , Sanchari Sinha Dutta , Kateryna Kon , Coronavirus Disease Covid 19 , Ars Cov 2 , Covid 19 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , Spike Protein ,

Researchers identify 25 new genetic markers linked to peptic ulcers

Researchers studied stomach and duodenal ulcers in a large research project comparing Japanese and European populations. ....

Yoichiro Kamatani , University Of Tokyo , Department Of Computational Biology , East Asian , Computational Biology , Medical Sciences , Peptic Ulcer , Helicobacter Pylori , Research Project , Small Intestine ,

The association between viral infections and glioma risk

The causal relationship between viral infection and glioma. ....

Lightspring Shutterstock , World Health Organization , Varicella Zoster Virus , Herpes Zoster , Ars Cov 2 ,