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Novel genetic associations with anxiety unveiled in comprehensive study of over 1.2 million people

The genetic basis of anxiety disorders, identify genetic loci, and calculate polygenic risk scores for anxiety. ....

United States , Ancestry Association Study , Us Research Program Ao , Gene Discovery , Biological Insights , Anxiety Disorders , Multi Ancestry Genome Wide Association Study , Image Credit , South Asia , East Asian , Million Veteran Project , United Kingdom Biobank , Anxiety Disorder , Mental Health ,

NIH-funded research enhances genetic testing for health equity

To prevent an emerging genomic technology from contributing to health disparities, a scientific team funded by the National Institutes of Health has devised new ways to improve a genetic testing method called a polygenic risk score. ....

United Kingdom , United States , Niall Lennon , Nih National Human Genome Research Institute , Electronic Medical Health Records , Broad Institute In Cambridge , Us Research Program , National Institutes Of Health , National Human Genome Research , National Institutes , Nature Medicine , Broad Institute , Medical Health Records , Health Disparities ,

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease. ....

United States , Briana Van Treeck , Van Treeck , Jeremy Mcintyre , Eva Nogales , Akanksha Thawani , Justin Shumate , Connor Horton , Kathleen Collins , Xiaozhu Zhang , University Of California , Department Of Molecular , Kay Curci Foundation , National Institutes Of Health , Howard Hughes Medical Institute , Ruth Schubert Family , Distinguished Professor , Cell Biology , Nature Biotechnology , Sarah Palm , National Institutes , Kay Curci , Addition Therapeutics , Gene Therapy , Junk Dna , Cell Biology ,

Novel genetic locations associated with primary open-angle glaucoma identified

An international genetic study using multiancestry biobanks has identified novel genetic locations associated with primary open-angle glaucoma (POAG), the most common type of glaucoma and the leading cause of irreversible blindness globally. ....

United States , Milam Brantley Jr , Eric Gamazon , Barbarah Ellis , Xue Zhong , Karen Joos , Peter Straub , Nancy Cox , Jibril Hirbo , Global Biobank Initiative , Glaucoma Service , Vanderbilt Eye Institute , William Black Research Funds , Vanderbilt University Medical Center , National Institutes Of Health , Research To Prevent Blindness , Vanderbilt Genetics Institute , Centers For Disease , University Medical , Cell Reports Medicine , Genetic Medicine , Disease Control , Black Americans , Global Biobank Meta Analysis Initiative , Family Professor , Vanderbilt Eye ,

Husker research duo selected as Phase 1 winners in the NIH's Targeted Genome Editor Delivery Challenge

A Husker research duo was named a first-round winner in a National Institutes of Health competition aimed at generating solutions for delivering genome-editing technology to the cells of people with rare and common diseases. ....

United States , Janos Zempleni , Jiantao Guo , National Institutes Of Health , Roche Inc , University Of Nebraska , Utah State University , Nebraska Center , National Institutes , Willa Cather Professor , Genome Editor Delivery , Obesity Diseases , Integrated Biomolecular , Extracellular Vesicles , Gene Editing ,