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Patients with early breast cancer and negative ultrasound axillary lymph node staging had similar locoregional relapse and distant DFS at 5 years whether or not they received SLN biopsy.
An expert panel recommended a risk-stratified approach to screening, but the jury is still out for gene expression profile testing.
Risk factors for melanoma in children are like those in adults, and include a family history of melanoma, large/giant congenital nevi, and the presence of many atypical appearing nevi.