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Researchers have found that older adults suffering from depression age faster than their peers. Researchers at the University of Connecticut Center on Aging have found that older adults with depression age faster than their peers. This accelerated biological aging is associated with poor physical
For older adults whose depression persisted while taking an antidepressant, adding aripiprazole had greater benefits than switching to another antidepressant.
For older patients with resistant depression who fail to respond to antidepressants, the addition of atypical antipsychotic aripiprazole is superior to switching antidepressants, new research suggests.
A total of 619 patients were randomly assigned to augmentation of existing antidepressant medication with aripiprazole, augmentation with bupropion, or a switch from existing antidepressant medication to bupropion.
Adding an antipsychotic to an antidepressant they're already taking may offer a better way to help older adults with hard-to-treat depression.