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Epigenetic mechanisms, which are sensitive to environmental factors, function like a dimmer switch on our genes, controlling how much of the gene is expressed and how much is turned off over time, says first author Alexandre A. Lussier, research fellow at Massachusetts General Hospital
In an analysis of changes in epigenetic patterns in children and adolescents, researchers found that ages 3 through 5 is a potentially critical period for the biological embedding of childhood adversity that manifests in adolescence.
Researchers have identified various genes whose expression in the brain before birth may affect the risk of developing a range of mental illnesses during childhood. The team, which was led by investigators at Massachusetts General Hospital (MGH), a founding member of Mass General Brigham (MGB), published their findings recently in Nature Neuroscience.
The expression of certain genes in the brain before birth could influence the risk of developing various mental illnesses during childhood.
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