HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors
Pancreatic cancer is one of the deadliest cancers-;only about one in eight patients survives five years after diagnosis.
Source: news-medical.net
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"Super-enhancer" super-charges pancreatic tum
Salk scientists identified new set of molecules that drive the growth of human pancreatic cancer cell lines, explaining how genetic mutations can activate genetic "super-enhancers" that promote out-of-control pancreatic cancer growth. They show the efficacy of an experimental drug that targets a super-enhancer related protein, demonstrating the promise of therapeutics that block the effects of super-enhancers.
Source: eurekalert.org