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The first in-human clinical trial of a vaccine against the deadly Nipah virus has been launched by Oxford.

World Immunisation Week activities will culminate with a hybrid seminar on ‘Maternal participation in vaccine trials’, chaired by Dr Luisa Enria from LSHTM. ​​Pregnant and breastfeeding women are often automatically excluded from global vaccine research, development, and deployment during epidemics, despite being at elevated risk.  

Around 5,500 people with severe developmental disorders now know the genetic cause of their condition, thanks to a major nationwide study in the U.K. that will help improve diagnosis across the world.

More than 13,500 families from 24 regional genetics services across the UK and Ireland were recruited to the Deciphering Developmental Disorders (DDD) study. All the families had children with a severe developmental disorder, which was undiagnosed despite prior testing through their national health service and likely to be caused by a single genetic change. Combined with other high-tech methods, the team have so far been able to provide genetic diagnoses for around 5,500 children. The diagnoses were in over 800 different genes, including 60 new conditions previously discovered by the study.

Experts monitor patients for days, or even months, to reach a decision – there is no easy litmus test, says Mehrunisha Suleman, director of medical ethics at the University of Oxford