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Study uncovers cryptic vulnerabilities in RET oncogene that could aid in anti-cancer drug design

RET is a receptor protein with tyrosine kinase activity that can transfer a phosphate group from ATP to other molecules modifying their shape and function in signaling pathways that are essential to organogenesis and tissue maintenance. ....

Ivan Plaza Menacho , Emily Henderson , Cancer Group , Spanish National Cancer Research Centre , Experimental Therapeutics Programme , Protein Phosphorylation ,

Patient Biopsy Screening Platform Identifies Potential Drug Candidates against Brain Metastases

CNIO researchers claim the new METPlatform is simple, fast, cheap, and “infinitely superior to other screening methods.” ....

Manuel Valiente , National Cancer Research Centre , Experimental Therapeutics Programme , Brain Metastasis Group ,

New METPlatform allows researchers to test drugs for possible use in brain metastases

It is estimated that about a quarter of cancer patients are at risk of brain metastases, a rate that is increasing especially among those who suffer relapses after having undergone different cancer treatments. ....

Castilla La Manacha , Complejo Hospitalario Universitario , Cunqueiro Complejo Hospitalario , Eva Ortega Pa , Manuel Valiente , Emily Henderson , National Cancer Research Centre , Spanish Ministry Of Science , Breast Cancer Clinical Research Unit , Cancer Research Institute , Health Institute , National Brain Metastasis Network , Melanoma Research Alliance , Worldwide Cancer Research , Experimental Therapeutics Programme , Brain Metastasis Group , Beug Foundation , European Research Council , Spanish Cancer Association , European Fund For Regional Development , Hospital Universitario , Hospital Universitario De La Princesa , Complejo Hospitalario De Vigo , Hospital Universitario De Burgos , Unidad De Investigaci , Complejo Hospitalario Universitario De Albacete ,

Repressing a protein that facilitates DNA repair to potentiate chemotherapy

Repressing a protein that facilitates DNA repair to potentiate chemotherapy
news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.

United States , Luis Blanco , Severo Ochoa , Emily Henderson , Replication Group , Experimental Therapeutics Programme , Washington University St Louis , Centro De Biolog , Molecular Severo Ochoa , Washington University , Therapeutics Programme , ஒன்றுபட்டது மாநிலங்களில் , லூயிஸ் ப்ளான்க்கோ , சேவேரோ ஆசோவ , எமிலி ஹென்டர்சன் , பிரதிசெய்கை குழு , வாஷிங்டன் பல்கலைக்கழகம் ஸ்டம்ப் லூயிஸ் , மூலக்கூறு சேவேரோ ஆசோவ , வாஷிங்டன் பல்கலைக்கழகம் ,

CNIO researchers discover that a protein that facilitates DNA repair may potentiate chemotherapy

CNIO researchers discover that a protein that facilitates DNA repair may potentiate chemotherapy
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

United States , Luis Blanco , Selena Blanco , Massimo Lopes , Severo Ochoa , Patricia Ubieto , Daniel Gonz , European Regional Development Fund , Spanish Ministry Of Science , Replication Group , University Of Zurich Switzerland , Experimental Therapeutics Programme , Washington University St Louis , Swiss National Science Foundation , European Research Council , National Institute Of Health Carlos , Centro De Biolog , Molecular Severo Ochoa , Washington University , Therapeutics Programme , Score Unit , Spanish Ministry , National Institute , Health Carlos , European Research , ஒன்றுபட்டது மாநிலங்களில் ,