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Olaratumab Antibody Licensed from Lilly Demonstrates Proof of Concept as a Theranostic Radiopharmaceutical

MELBOURNE, Australia, April 17, 2023 /PRNewswire/ Telix Pharmaceuticals Limited (ASX: TLX, Telix, the Company)today announces successful preclinical development of radiolabelled olaratumab, an antibody licensed from Eli Lilly and Company (Lilly). Telix has demonstrated proof-of-concept (PoC) of using olaratumab to selectively deliver both diagnostic and therapeutic radiation to tumours as a radiopharmaceutical moiety and has produced a candidate for clinical translation. Telix will now progress to first-in-human clinical studies based on these highly encouraging results. In April 2022, Telix secured the exclusive worldwide rights to develop and commercialise radiolabelled forms of olaratumab for the diagnosis and treatment of human cancers.[1] Olaratumab was originally developed as a naked (non-radiolabelled) monoclonal antibody targeting Platelet Derived Growth Factor Receptor Alpha (PDGFR), a target expressed in multiple tumour types. Olaratumab has a well-established clinical safe ....

United Kingdom , United States , Eli Lilly , Michael Wheatcroft , Kyahn Williamson , American Cancer Society , Australian Securities Exchange , Health Canada , Prnewswire Telix Pharmaceuticals Limited , Corporate Communications , Drug Administration , Company Lilly , Telix Pharmaceuticals Limited Disclosure Committee , Telix Pharmaceuticals , Australian Therapeutic Goods Administration , Pharmaceuticals Limited , Platelet Derived Growth Factor Receptor Alpha , Soft Tissue Sarcoma , Positron Emission Tomography , Chief Scientist , Telix Pharmaceuticals Limited , Cancer Society , Adv Med , April 17 , 023 Prnewswire Telix Pharmaceuticals Limited Asx Tlx , He Company Today Announces Successful Preclinical Development Of Radiolabelled Olaratumab ,

SECUNET SECURITY AG : Warburg Research gives a Buy rating

Felix Ellmann from Warburg Research retains his positive opinion on the stock with a Buy rating. The target price continues to be set at EUR 375. | April 14, 2023 ....

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