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Chinese NMPA Approves Pivotal Phase III Study of TLX591-CDx for Prostate Cancer Imaging

MELBOURNE, Australia, Oct. 17, 2022 /PRNewswire/ Telix Pharmaceuticals Limited (ASX: TLX, Telix, the Company)today announces that the Chinese National Medical Products Administration (NMPA) Center for Drug Evaluation (CDE) has approved an investigational new drug (IND) application to commence a pivotal Phase III registration study of TLX591-CDx (Kit for the preparation of 68Ga-PSMA-11), for the imaging of prostate cancer using Positron Emission Tomography (PET) that will bridge to the marketing authorisation granted to Illuccix by the United States Food and Drug Administration (FDA). The IND application was submitted in partnership with Grand Pharmaceutical Group Limited (Grand Pharma), Telix's partner in the Greater China region. The bridging study is required to provide data obtained in a Chinese population to establish that the diagnostic efficacy of TLX591-CDx is equivalent in Chinese and Western populations. This study will enroll up to 110 patients with suspected recurrent ....

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Broadly neutralizing antibodies are the blueprint for variant-proof, pansarbecovirus vaccines

A recent Nature Reviews Immunology study has summarized the efficacy of neutralizing antibodies that target four main regions of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), namely, the receptor-binding domain (RBD) in the S1 subunit, the fusion peptide region in the S2 subunit, the stem helix region, and the N-terminal domain. ....

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iTWire - felix delivers quality calls with VoLTE and Wi-Fi calling

Felix, a mobile and internet brand under telecommunications company TPG Telecom, has introduced VoLTE and Wi-Fi calling to improve call connections, q. ....

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The Lowveld welcomes Felix, the only IT hire you will ever need

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lowvelder.co.za - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from lowvelder.co.za Daily Mail and Mail on Sunday newspapers.

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A novel method to identify spike stabilizing mutations for COVID-19 vaccine development

Researchers discuss a robust method to identify mutations that improve the expression and stabilize the conformation of the SARS-CoV-2 spike protein. ....

Extended Data Table , Coronavirus Disease Covid 19 , Amino Acid , Flow Cytometry , Protein Expression , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,