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Obecabtagene Autoleucel (obe-cel, AUTO1) for Relapsed/Refractory Adult B-Cell Acute Lymphoblastic Leukemia (R/R B-ALL): Pooled Analysis of the Ongoing FELIX Phase Ib/II Study

Claire Roddie, MD, PhD, presents data from the pooled analysis of the ongoing FELIX phase Ib/II study investigating obecabtagene autoleucel in patients with relapsed/refractory adult B-cell acute lymphoblastic leukemia.

San-diego , California , United-states , Philadelphia , Pennsylvania , Obecabtagene-autoleucel , Claire-roddie , Pooled-analysis , Clin-oncol , Median-dor , Felix-study

Obe-Cel Elicits High Remission Rates in R/R B-ALL Irrespective of Leukemic Burden

Obecabtagene autoleucel elicited durable responses in patients with relapsed or refractory B-cell acute lymphoblastic leukemia independent of leukemic burden at lymphodepletion, although better outcomes were observed in those with lower burden.

United-states , United-kingdom , American , Claire-roddie , American-society-of-clinical-oncology-annual-meeting , University-college-london , Clinical-oncology-annual-meeting , Obe-cel , Obecabtagene-autoleucel , Cart-cell-therapy , B-cell-acute-lymphoblastic-leukemia , Leukemia