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SARS-CoV-2 may join the ranks of mild cold-causing coronaviruses What is the endgame for SARS-CoV-2, the virus that is causing worldwide devastation? If it becomes endemic -- circulating in the general population -- and most people are exposed in childhood, SARS-CoV-2 may join the ranks of mild cold-causing coronaviruses that currently circulate in humans, according to a model developed by Emory and Penn State scientists. The model, published January 12 in Science, draws upon studies of the four common cold coronaviruses and SARS-CoV-1. For those viruses, the term "herd immunity" is incomple...

Older adults with cognitive impairment who live alone are hit hard by pandemic The pandemic has exacerbated isolation and fears for one very vulnerable group of Americans: the 4.3 million older adults with cognitive impairment who live alone. As the coronavirus continues to claim more lives and upend others, researchers led by UC San Francisco are calling for tailored services and support for older adults living alone with memory issues, who are experiencing extreme isolation, and are exposed to misinformation about the virus and barriers to accessing medical care. In their qualitative study,...

Researchers identify natural products with potential to disrupt viral spread Researchers at Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have broken down the genomic and life history traits of three classes of viruses that have caused endemic and global pandemics in the past and identify natural products - compounds produced in nature - with the potential to disrupt their spread. In a review appearing in the Journal of Natural Products, marine chemists Mitchell Christy, Yoshinori Uekusa, and William Ge...

Scientists identify distinct sub-types of angiosarcomas to allow for targeted treatment A new study led by clinician-scientists from the National Cancer Centre Singapore (NCCS), with collaborators from research institutions worldwide, has found that angiosarcomas have unique genomic and immune profiles which allow them to be classified into three different subtypes. With this new and improved classification system, patients can be treated using a personalized-medicine approach and it will encourage the development of novel treatments. Angiosarcomas, a type of cancer that forms in the lining o...

Model to assess the effect of lockdowns has fundamental shortcomings In a recent study, researchers from Imperial College London developed a model to assess the effect of different measures used to curb the spread of the coronavirus. However, the model had fundamental shortcomings and cannot be used to draw the published conclusions, claim Swedish researchers from Lund University, and other institutions, in the journal Nature. / nwT8_CyIcSI The results from Imperial indicated that it was almost exclusively the complete societal lockdown that suppressed the wave of infections in Europe during...