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Why quantifying Openness matters - The Official PLOS Blog

PLOS’ mission is to transform research communication for the good of science and society. We believe that Open Science is the key. Open Science supports rigor, reproducibility, inclusivity, and efficiency and in doing so, results in accelerated progress, stronger research, and increased trust in results. Increasing the prevalence of Open Science is a prerequisite to reaping the full benefits. ....

United Kingdom , Iain Hrynaszkiewicz , United Kingdom Reproducibility Network , Open Science , Open Science Indicators , Science Indicators , Natural Language Processing , Open Access , Charite Metrics Dashboard , French Open Science Monitor , Open Code , Accessible Data ,

Institutional dashboards on clinical trial transparency for University Medical Centers: A case study

Author summary Why was this study done? Clinical trials are the foundation of evidence-based medicine and should follow established guidelines for transparency: Their results should be available, findable, and accessible regardless of the outcome. Previous studies have shown that many clinical trials fall short of transparency guidelines, which distorts the medical evidence base, creates research waste, and undermines medical decision-making. University Medical Centers (UMCs) play an important role in increasing clinical trial transparency but are often unaware of their performance on these practices, making it difficult to drive improvement. What did the researchers do and find? We developed a pipeline to evaluate clinical trials across several established practices for clinical trial transparency and applied it in a cohort of 2,895 clinical trials led by German UMCs. We found that while some practices are gaining adherence (e.g., prospective registration in ClinicalTrials.gov i ....

United States , Hong Kong , Florian Naudet , Klinischer Studien , Martin Holst , Access Publication Fund Of Charit , Coalition On Advancing Research Assessment Co , Drug Administration Amendments , Ministry Of Education , University Medical Center , International Committee Of Medical Journal Editors , World Health Organization , University Medical Centers Umcs , European Commission Open Science , German Research Foundation , University Of Rennes , Declaration On Research Assessment , Research Of Germany , Agreement On Reforming Research Assessment , University Medical Centers , Medical Centers , German Clinical Trials Register , Trials Register , Creative Commons Attribution License , Federal Ministry , Consolidated Standards ,