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1. In a large prospective multicentre diagnostic accuracy study, magnetically guided capsule endoscopy with a detachable string (ds-MCE) demonstrated high accuracy and safety in the detection and grading of esophagogastric varcies in patients with cirrhosis. Evidence Rating: 1 (Excellent) Esophagogastric varices are highly prevalent in patients with cirrhosis and are a major cause of mortality ....
Early vs Late Fixation of Extremity Fractures Among Adults With Traumatic Brain Injury 1. In a cohort of patients with traumatic brain injury, early fixation of extremity fractures within 24 hours of injury was not associated with greater rates of unfavourable functional outcomes at 6 months. Evidence Rating: 2 (Good) While extremity fractures are commonly ....
1. In this randomized controlled trial, among patients with primary biliary cholangitis (PBC) who had had inadequate response to ursodeoxycholic acid, seladelpar was superior to placebo in achieving biochemical response and symptomatic management. 2. Seladelpar had an acceptable safety profile, with similar rates of adverse events to a placebo. Evidence Rating Level: 1 (Excellent) Study ....
1. The risk of cardiovascular disease (CVD) and all-cause death for individuals with type 2 diabetes mellitus (T2DM) is increased for those with non-alcoholic fatty liver disease (NAFLD) compared to those without NAFLD. Evidence Rating Level: 2 (Good) Non-alcoholic fatty liver disease (NAFLD) is increasing in prevalence globally. Patients with NAFLD are at an increased ....
Sergio Giralt, MD, leads a discussion on the importance of a multidisciplinary team approach in caring for patients with VOD, from recognizing early signs to treating and monitoring the disease. ....