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[Full text] Management of Sickle Cell Disease Complications Beyond Acute Chest Syn
Parvovirus –B19 is an erythrotropic virus that selectively targets human red blood cells and their precursors. 29 In patients with SCD, this can lead to life-threatening anemia due to abrupt cessation of erythropoiesis. Features are new or worsening signs of anemia, with an acute drop in hemoglobin and reticulocytopenia in the absence of blood loss or sequestration. Urgent recognition and transfusion are necessary to prevent circulatory failure and death. Splenic Complications Streptococcus pneumoniae, Neisseria meningitides and Salmonella species, leaving patients prone to life-threatenin...
Source: dovepress.com