Page 9 - Gene Expression News Today : Breaking News, Live Updates & Top Stories | Vimarsana

Chromatin accessibility is essential in regulating gene expression and cellular identity, and alterations in accessibility have been implicated in driving cancer initiation, progression and metastasis1–4. Although the genetic contributions to oncogenic transitions have been investigated, epigenetic drivers remain less understood. Here we constructed a pan-cancer epigenetic and transcriptomic atlas using single-nucleus chromatin accessibility data (using single-nucleus assay for transposase-accessible chromatin) from 225 samples and matched single-cell or single-nucleus RNA-sequencing exp...

Research finds younger African American women with triple-negative breast cancer may have a molecularly distinct form of the disease that makes it more aggressive.

Resverlogix Corp. today announced the publication of a peer-reviewed article, entitled Apabetalone, a Clinical-stage, Selective BET Inhibitor, Opposes DUX4 Target Gene Expression in Primary Human...

Download this Gene Expression and Regulation eBook to explore how next-generation sequencing (NGS) is accelerating high impact studies using bulk or single-cell RNA-Seq applications.

Salk scientists identified new set of molecules that drive the growth of human pancreatic cancer cell lines, explaining how genetic mutations can activate genetic "super-enhancers" that promote out-of-control pancreatic cancer growth. They show the efficacy of an experimental drug that targets a super-enhancer related protein, demonstrating the promise of therapeutics that block the effects of super-enhancers.