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Newly Engineered Bacterium can Produce Carminic Acid Written by AZoMApr 7 2021 A team of researchers from the Korea Advanced Institute of Science and Technology (KAIST) has designed a bacterium that can produce carminic acid—a natural red colorant that is extensively used in cosmetics and food. A schematic biosynthetic pathway for the production of carminic acid from glucose. Biochemical reaction analysis and computer simulation-assisted enzyme engineering were employed to identify and improve the enzymes (DnrFP217K and GtCGTV93Q/Y193F) responsible for the latter two reactions. Image Credit...

 E-Mail IMAGE: Figure: A schematic biosynthetic pathway for the production of carminic acid from glucose. Biochemical reaction analysis and computer simulation-assisted enzyme engineering was employed to identify and improve the enzymes (DnrFP217K... view more  Credit: KAIST A research group at KAIST has engineered a bacterium capable of producing a natural red colorant, carminic acid, which is widely used for food and cosmetics. The research team reported the complete biosynthesis of carminic acid from glucose in engineered Escherichia coli. The strategies will be useful for the de...