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Study finds previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease

Researchers explored the effects of a small humanin-like peptide 2 (SHLP2) variant on mitochondrial function. ....

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Previously unidentified protein variant shields against Parkinson's disease

A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis School of Gerontology study. ....

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"Genetic priority score" promises to revolutionize drug development

Driven by the need for a better way to prioritize targets for drug development, the Icahn School of Medicine at Mount Sinai has led the development of a novel "genetic priority score" (GPS) that will integrate various types of human genetic data into a single easy-to-interpret score. ....

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Researchers develop a framework to identify potentially hidden genetic contributors to disease

Genome-wide association studies (GWAS) on patient blood samples are useful for identifying the genetic basis of blood cell traits and their links to common diseases. ....

Caluma Macrae , Division Of Cardiovascular Medicine , Mass General Brigham ,

Study uncovers unique genetic diversity in Australian Indigenous populations

Scientists at ANU have revealed significant genetic diversity among Australian Indigenous communities, uncovering unique genetic variations that could impact personalized medical treatments for chronic diseases. ....

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