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Uncovering Rare Genetic Insights Sheds Light on Health Disparities in Inflammatory Bowel Disease (IBD)

The advent of whole genome sequencing technology has prompted an explosion in research into how genetics are associated with disease risk. But the vast majority of genetics research has been done on people of European ancestry, and genetics researche

United-states , Georgia , Emory-university , Americans , Greg-gibson , Subra-kugathasan , Marie-patton , Gibson , Genetics-consortium , Georgia-tech , Regent-professor , Marie-patton-chair

Genetics study shines light on health disparities for IBD

Genetics study shines light on health disparities for IBD
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Emory-university , Georgia , United-states , Americans , Subra-kugathasan , Marie-patton , Greg-gibson , School-of-biological-sciences , Genetics-consortium , Gibson , Georgia-tech , Regent-professor

New study investigates role of rare gene variants in IBD risk for African Americans

The advent of whole genome sequencing technology has prompted an explosion in research into how genetics are associated with disease risk.

Georgia-institute-of-technology , Georgia , United-states , Emory-university , Americans , Marie-patton , Greg-gibson , Subra-kugathasan , School-of-biological-sciences , Genetics-consortium , Gibson , Georgia-tech

Genetics study shines light on health dispari

<p>In a new study, researchers at the Georgia Institute of Technology investigated whether 25 rare gene variants known to be associated with inflammatory bowel disease (IBD) play a role in risk for African Americans. While the rare variant associations were recently discovered in individuals of European ancestry, contributing to about 15% of cases, it was unknown if and how those same rare gene variants might affect risk for African Americans.</p>

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A rare genetic spotlight on health disparities for inflammatory bowel disease

A rare genetic spotlight on health disparities for inflammatory bowel disease
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Emory-university , Georgia , United-states , Americans , Greg-gibson , Subra-kugathasan , Marie-patton , Gibson , Genetics-consortium , A-rare-genetic-spotlight-on-health-disparities , School-of-biological-sciences , Genome-medicine

Does inflammatory bowel disease have a causal relationship with extracolonic tumors?

Whether inflammatory bowel disease (IBD) is causally related to extracolonic cancers.

United-kingdom , Orawan-pattarawimonchai-shutterstock , Genetics-consortium , United-kingdom-biobank , Inflammatory-bowel-disease , Reast-cancer , Ancer , Rohn-39s-disease , Enetic , Enetics , Enome , Nflammation

New Study Sheds Light on the Cause of Severe Inflammatory Bowel Disease

Scientists at Cedars-Sinai have identified a genetic variant that is associated with perianal Crohn's disease. Investigators at Cedars-Sinai have discovered a genetic variant that elevates an individual's likelihood of experiencing perianal Crohn's disease, which is considered to be the most severe

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New study sheds light on cause of severe inflammatory bowel disease

Perianal Crohn’s disease is a type of inflammatory bowel disease that affects the area around the anus. It can cause symptoms such as pain, itching and discharge, as well as more serious complications such as abscesses and fistulas. Scientists at Cedars-Sinai have identified a genetic mutation associated with perianal Crohn’s disease. Investigator Cedars Sinai […]

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Genetic Variant Linked with Severe Manifestation of Crohn's Disease

Findings suggest that targeting the alternative complement pathway may be a novel therapeutic approach for treating perianal Crohn’s disease.

Dermot-mcgovern , Talin-haritunians , Lisaz-greer , Kathrin-michelsen , Perianal-crohn , Immunobiology-research-institute , Helmsley-alliance-for-research-excellence , Sinai-medical-center , Sinaif-widjaja-foundation-inflammatory-bowel , Genetics-consortium , Mcgovern-laboratory , Research-repository

Genetic Analysis Links GERD to IPF

Three of the comorbidities examined appeared to be causally associated with an increased risk of IPF.

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