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White-tailed deer susceptible to SARS-CoV-2 infection, study finds


White-tailed deer susceptible to SARS-CoV-2 infection, study finds
A team of scientists from the United States has recently demonstrated that white-tailed deer are highly susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Moreover, the infected animals are capable of transmitting the virus to their non-infected counterparts via indirect contact. The study is currently available on the
Background
Although there is uncertainty about the exact origin of SARS-CoV-2, a pathogen spillover from animals to humans is likely responsible for the emergence of coronavirus disease 2019 (COVID-19) pandemic. Genomic analysis studies have revealed that SARS-CoV-2 shares high genetic similarities with coronaviruses found in bats, especially horseshoe bats. However, current evidence indicates that the virus might have transmitted from an animal source to humans via an intermediate host. Although initially it was hypothesized that pangolins are the int ....

United States , Sanchari Sinha Dutta , Warren Metcalf Shutterstock , Warren Metcalf , Image Credit , Coronavirus Disease Covid 19 , Sars Cov 2 , Corona Virus , Lymph Nodes , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ஒன்றுபட்டது மாநிலங்களில் , சஞ்சரி சீன்ஹா தத்தா , வாரன் மெட்‌க்யாஃப் , படம் கடன் , கொரோனா வைரஸ் , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

New tests may help reveal the transcriptome of SARS-CoV-2 and predict disease course

As the COVID-19 pandemic continues to infect people in their hundreds of thousands around the world, a new study describes a panel of novel tests for genomic (g) and subgenomic (sg) mRNAs generated by SARS-CoV-2. Most assays in use at present are either qualitative or semi-quantitative, and cannot evaluate the transcription molecules in detail. ....

Liji Thomas , Coronavirus Disease Covid 19 , Sars Cov 2 , Corona Virus , Gene Expression , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , கொரோனா வைரஸ் , கீந் வெளிப்பாடு , சர்வதேச பரவல் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Intranasal vaccination effectively reduces viral shedding of SARS-CoV-2 in monkeys

A new preprint that appeared on the bioRxiv server reports that intranasal vaccination with the D614G variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in rhesus monkeys reduces viral shedding. This is an experiment in non-human primates (NHP), and its extrapolation to humans is unclear as yet. ....

Liji Thomas , Sars Cov 2 , Corona Virus , Coronavirus Disease Covid 19 , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Researchers identify biomarkers in sperm for paternal offspring autism susceptibility


Researchers identify biomarkers in sperm for paternal offspring autism susceptibility
Biomarkers in human sperm have been identified that can indicate a propensity to father children with autism spectrum disorder. These biomarkers are epigenetic, meaning they involve changes to molecular factors that regulate genome activity such as gene expression independent of DNA sequence, and can be passed down to future generations.
In a study published in the journal
Clinical Epigenetics on Jan. 7, researchers identified a set of genomic features, called DNA methylation regions, in sperm samples from men who were known to have autistic children. Then in a set of blind tests, the researchers were able to use the presence of these features to determine whether other men had fathered autistic children with 90% accuracy. ....

Michael Skinner , Emily Henderson , Washington State University , Professor Of Biological Sciences , Valencia University , Valencia Clinical Research Center , Clinical Epigenetics , Biological Sciences , Dna Methylation , Gene Expression , மைக்கேல் ஸ்கின்னர் , எமிலி ஹென்டர்சன் , வாஷிங்டன் நிலை பல்கலைக்கழகம் , ப்ரொஃபெஸர் ஆஃப் உயிரியல் அறிவியல் , வலென்சியா பல்கலைக்கழகம் , வலென்சியா மருத்துவ ஆராய்ச்சி மையம் , உயிரியல் அறிவியல் , மன இறுக்கம் , கீந் வெளிப்பாடு ,