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New RNA-seq, metabolomics protocol offers mor

Van Andel Institute scientists have developed a new extraction protocol for RNA-seq and metabolomic analysis, offering a more complete picture of cellular activity than either technique on its own. The protocol employs a streamlined extraction from a single sample, which reduces variation, improves efficiency, preserves data fidelity and maximizes use of precious biospecimens. ....

United States , Grand Rapids , Zacharyb Madaj , Christine Isaguirre , Marie Adams , Russellg Jones , Vijayvardhan Kamalumpundi , Scotta Givan , Michaels Dahabieh , Rebeccaa Siwicki , Van Andel , Marthal Escobar Galvis , Abigaile Ellis , Brejnev Muhire , Bryan Sheldon , Institute Mass Spectrometry Core , Method Of Research , Department Of Metabolism , Van Andel Institute , Score Technologies , Lisa Decamp , Mass Spectrometry Core , Biorepository Core , Biostatistics Core , Genomics Core , Mandel Institute ,

Welcome to the golden age of the genome

Whole genome sequencing is now becoming cheap enough that doctors will be able to order it for everyone if they want. That could lead to truly personalized medicine. But it could be even bigger than that. ....

Sean Vargas , Claudia Satizabal , Bonnie Petrie , University Of Texas At San Antonio , Ut Health San Antonio , Department Of Public Health Sciences , Genomics Core , San Antonio , Public Health Sciences ,

How the Placement of a Gene Affects Its Expression

Genomes are made up of thousands of individual pieces – genes – which are expressed at different levels. Researchers at EMBL have shed light on how the placement of a gene affects its expression, as well as that of its neighbours. ....

Mitchell Leslie , Richard Feynman , Oxford Nanopore Grid , Jef Boeke , Hughes Amanda , Amanda Hughes , Lars Steinmetz , Aaron Brooks , Steinmetz Lars , Boeke Jef , Steinmetz Group , Volkswagen Foundation Life , Volkswagen Foundation , Genomics Core , Oxford Nanopore ,