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What we know so far about COVID-19 variants worldwide

What we know so far about COVID-19 variants worldwide
© Kena Betancur/AFP via Getty Images, FILE
Scientists around the world are on the lookout for new COVID-19 variants, which are caused by mutations of the virus when its replication machinery makes an error. Experts say these mutations and the new variants are normal and to be expected.
In recent months, so-called variants of concern have been identified in the U.K., South Africa, Brazil and in the U.S. And it s not a coincidence they re appearing in these countries, which have been overwhelmed by the sheer number of COVID-19 cases. ....

New York , United States , United Kingdom , White House , District Of Columbia , Discovery Center , San Francisco Bay , South Africa , San Diego , The White House , Sharp Coronado Hospital , South African , David Montefiori , Anthony Fauci , Joe Biden , Anthonys Fauci , Patrick Vallance , Mandel Ngan , Kena Betancur , Jasmine Plummer , Charles Chiu , Centers For Disease , National Institute Of Allergy , National Strategy , Clinical Microbiology Laboratory , Duke University Medical Center ,

What we know so far about COVID-19 variants in the US, UK and worldwide

UK variant (B.1.1.7)
The U.K. variant was one of the first identified variants of concern. It s estimated to have first emerged in September, and it quickly gained a foothold, spreading like wildfire throughout the U.K. and then other parts of the world. At least 293 cases have been reported in the U.S., according to the Centers for Disease Control and Prevention, which said the actual tally probably exceeds that.
There s good evidence this variant is more transmissible, spreading more easily and more quickly. This increased transmissibility is believed to be due to mutations in the spike protein the part of the virus that allows it to stick to cells. This spike protein is what the vaccines target. ....

San Francisco Bay , United States , South Africa , United Kingdom , South African , David Montefiori , Patrick Vallance , Anthony Fauci , Jasmine Plummer , Joe Biden , Charles Chiu , Centers For Disease , Clinical Microbiology Laboratory , Duke University Medical Center , National Institute Of Allergy , Discovery Center , Disease Control , National Institute , Infectious Diseases , President Joe Biden , Duke University Medical , Amazonian Manaus , Francisco Bay Area , Francisco Bay Area Variant , Bay Area , Abbott Viral Diagnostics ,

COVID-19 variants: What we know about mutants in the US, UK and worldwide

UK variant (B.1.1.7)
The U.K. variant was one of the first identified variants of concern. It s estimated to have first emerged in September, and it quickly gained a foothold, spreading like wildfire throughout the U.K. and then other parts of the world. At least 293 cases have been reported in the U.S., according to the Centers for Disease Control and Prevention, which said the actual tally probably exceeds that.
There s good evidence this variant is more transmissible, spreading more easily and more quickly. This increased transmissibility is believed to be due to mutations in the spike protein the part of the virus that allows it to stick to cells. This spike protein is what the vaccines target. ....

San Francisco Bay , United States , South Africa , United Kingdom , South African , David Montefiori , Patrick Vallance , Anthony Fauci , Jasmine Plummer , Joe Biden , Charles Chiu , Centers For Disease , Clinical Microbiology Laboratory , Duke University Medical Center , National Institute Of Allergy , Discovery Center , Disease Control , National Institute , Infectious Diseases , President Joe Biden , Duke University Medical , Amazonian Manaus , Francisco Bay Area , Francisco Bay Area Variant , Bay Area , Abbott Viral Diagnostics ,

HKU chemists develop a new drug discovery strategy for

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IMAGE: Graphic illustration of the work: DNA-programmed affinity labelling (DPAL) enables the direct screening of DNA-encoded chemical libraries (DELs) against membrane protein targets on live cells to create novel drug discovery.
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Credit: The University of Hong Kong
A research team led by Dr Xiaoyu LI from the Research Division for Chemistry, Faculty of Science, in collaboration with Professor Yizhou LI from School of Pharmaceutical Sciences, Chongqing University and Professor Yan CAO from School of Pharmacy, Second Military Medical University in Shanghai has developed a new drug discovery method targeting membrane proteins on live cells.
Membrane proteins play important roles in biology, and many of them are high-value targets that are being intensively pursued in the pharmaceutical industry. The method developed by Dr Li s team provides an efficient way to discover novel ligands and inhibitors against membrane proteins, which rema ....

Hong Kong , Xiaoyu Li , University Of Hong Kong , Hong Kong General , Bryan Cao , Yiran Huang , Yizhou Li , Professor Of Research Division For Chemistry , Second Military Medical University , Centre For Panoromic Sciences , National Natural Science Foundation Of China , Nature Research Chemistry Community , Laboratory For Synthetic Chemistry , Nature Publishing Group , Technology Commission Of Hong Kong , Research Grants Council Of Hong Kong , School Of Pharmacy , School Of Pharmaceutical Sciences , Key Laboratory Of Synthetic Chemistry , Research Division For Chemistry , Research Division , Professor Yizhou , Pharmaceutical Sciences , Chongqing University , Professor Yan , Nature Chemistry ,

Chemists and collaborators develop a new drug discovery strategy for "undruggable" drug targets

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Chemists and collaborators develop a new drug discovery strategy for “undruggable” drug targets
Graphic illustration of the work: DNA-programmed affinity labelling (DPAL) enables the direct screening of DNA-encoded chemical libraries (DELs) against membrane protein targets on live cells to create novel drug discovery opportunities.
A research team led by Dr Xiaoyu LI from the Research Division for Chemistry, Faculty of Science, in collaboration with Professor Yizhou LI from School of Pharmaceutical Sciences, Chongqing University and Professor Yan CAO from School of Pharmacy, Second Military Medical University in Shanghai has developed a new drug discovery method targeting membrane proteins on live cells. ....

Hong Kong , Xiaoyu Li , University Of Hong Kong , Hong Kong General , Bryan Cao , Yiran Huang , Yizhou Li , Professor Of Research Division For Chemistry , Second Military Medical University , Centre For Panoromic Sciences , National Natural Science Foundation Of China , Laboratory For Synthetic Chemistry , Nature Publishing Group , Technology Commission Of Hong Kong , Research Grants Council Of Hong Kong , School Of Pharmacy , School Of Pharmaceutical Sciences , Key Laboratory Of Synthetic Chemistry , Research Division For Chemistry , Research Division , Professor Yizhou , Pharmaceutical Sciences , Chongqing University , Professor Yan , Nature Chemistry , Professor Yan Cao ,