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Significant genetic variations linked to cannabis use disorder identified in major global ancestries

Multi-ancestry genome-wide association study of cannabis use disorder. ....

United States , Lumppini Shutterstock , Brigham Biobank , Consortium Of Alcohol , Million Veteran Program , Psychiatric Genomics Consortium , Nature Genetics , Mass General Brigham Biobank , Admixed American , East Asian , Sequencing Consortium , Nicotine Use , Nicotine Dependence , Chronic Pain , Lung Cancer ,

AHRI partners with BGI Genomics to boost its genomics and precision medicine capabilities

On October 13, 2023, in Addis Ababa, Armauer Hansen Research Institute (AHRI) and BGI Genomics signed a Memorandum of Understanding to enhance the Institute's genomics and precision medicine capabilities. ....

Gerhard Henrik Armauer Hansen , Afework Kassu , Addis Ababa , Armauer Hansen Research Institute , Ethiopian Ministry Of Health , Ethiopian Ministry , Precision Medicine ,

'A trillion in each of us': Flagship-backed Quotient takes on somatic genomics

Launching a company based on knowledge that “the fundamental principle that most people hold to be true is off by a trillion” is a rare opportunity, said Jake Rubens, co-founder and president of Quotient Therapeutics Inc., a company that emerged from stealth this week, backed by two years of platform development and a $50 million investment from Flagship Pioneering. ....

Jake Rubens , Quotient Therapeutics Inc , Quotient Sciences , Quotient Therapeutics Inc , Flagship Pioneering Inc ,

"Anchored phylogenomics and revised classification of the Miltogrammina" by Nikolas P. Johnston, Thomas Pape et al.

The Miltogramminae (Diptera: Sarcophagidae) includes ~600 species across >40 genera, which constitute ~20% of global Sarcophagidae. While molecular phylogenetic hypotheses have been produced for this group, critical problems persist, including the presence of paraphyletic genera, uncertain relationships between genera, a bias of sampling towards Palaearctic taxa, and low support for many branches. The present study remedies these issues through the application of Anchored Hybrid Enrichment (AHE) to a sample including ~60% of the currently recognised genera (16% of known species) representing all biogeographic regions except the Neotropical. An alignment of 1,281 concatenated loci was analysed with maximum likelihood (RAxML, IQ-TREE), Bayesian inference (ExaBayes) and coalescent-based approaches (ASTRAL, SVDquartets), which resulted in highly supported and concordant topologies, providing unprecedented insight into the relationships of this subfamily of flesh flies, allowing a major ....

Pterella Robineau Desvoidy , Aenigmetopia Malloch , Senotainia Macquart , Erioprocta Enderlein , Metopia Meigen , Miltogramma Meigen , Taxigramma Macquart , Metopodia Brauer Bergenstamm , Anchored Hybrid Enrichment , Metopodia Brauer , Ybrid Enrichment ,

Why 1 Health System Is Embedding Genomics Into Primary Care

At Northshore–Edward Elmhurst Health, all patients are offered genetic testing as part of their primary care visit. This helps clinicians create more personalized care plans and facilitates earlier disease diagnoses, said Kristen Murtos, the health system's chief innovation and transformation officer. ....

United States , Republic Of , Kristen Murtos , Edward Elmhurst Health , Swedish Hospital Foundation , Northshore University Healthsystem , Northshore Medical Group , Exact Sciences , Weight Loss , Medical Devices , Healthcare Innovation , Medcity News , Medcity News , San Francisco , Life Sciences , Rock Health , Startup Advice , Startup Funding , Patient Monitoring System , Otion Sensors , Healthcare It , Foodborne Pathogens , Iagnostics Company , Iagnostic Platforms , Minimally Invasive Surgery , Aser Surgery ,