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A direct lineage-typing RT-PCR assay reveals insights into the transition from Omicron BA.1 to BA.2 dominance in Sweden

Researchers monitored the remarkably rapid Omicron BA.1 to BA.2 sublineage dominance transition in the Swedish population in early 2022 on a day-to-day basis using a customized lineage-typing RT-PCR assay. ....

Centers For Disease , Disease Control , Coronavirus Disease Covid 19 , Polymerase Chain Reaction , Reverse Transcriptase , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

Heart failure arises from mutations in distinct genes, study finds

Heart failure is a common and devastating disorder for which there is no cure. Many cardiomyopathies -;conditions that make it difficult for the heart to pump blood such as dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM) -; can lead to heart failure, but treatments for patients with heart failure do not take these distinct conditions into account. ....

Christinee Seidman , Thomasw Smith , Jonathan Seidman , Emily Henderson , Division Of Cardiovascular Medicine , Harvard Medical School , Cardiovascular Genetics Center , Frederickh Bugher Foundation Professor Of Genetics , Cardiovascular Medicine , Co Corresponding Author , Foundation Professor , Heart Failure , Medical School , Na Sequencing ,