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New Vaccine Technology Produces More Antibodies Against SARS-CoV-2 in Mice

New Vaccine Technology Produces More Antibodies Against SARS-CoV-2 in Mice
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Caltech's New Vaccine Tech Boosts Covid Antibodies in Mice

Caltech's New Vaccine Tech Boosts Covid Antibodies in Mice
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Leesa Nakatomi , Kathryn Huey Tubman , Allen Vc Davis , Paulo Lin , Priyanthi Gnanapragasam , Caltech Milton , National Institutes Of Health , Merkin Institute Professor , Caltech Merkin Institute , Melinda Gates Foundation , Rothenberg Innovation Initiative , Merkin Institute , Richardn Merkin Institute For Translational Research , George Mason University Fast , Merkin Institute For Translational Research At Caltech , David Baltimore Professor , Biological Engineering , Magnus Hoffmann , National Institutes , Early Independence Award , Merkin Institute Fellow , Translational Research , Francis Clauser Doctoral Prize , Barbara Wold , Bren Professor , Molecular Biology ,

Protection, Accessibility, Durability

Protection, Accessibility, Durability
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United States , Joan Miller , Luk Vandenberghe , David Glendenning Cogan , Elisa Schwartz , Nerea Zabaleta Lasarte , George Mason University Fast , Us Centers For Disease , National Institutes Of Health , Melinda Gates Foundation , Harvard Medical School , Grousbeck Gene Therapy Center , University Of Pennsylvania , Grousbeck Gene Therapy Center At Mass Eye , Massachusetts Consortium For Pathogen Readiness Mass , Massachusetts Eye , Cell Host , Mass Eye , David Glendenning Cogan Professor , Massachusetts General Hospital , Zabaleta Lasarte , Mass General , Novartis Gene Therapies , Massachusetts Consortium , Pathogen Readiness , George Mason University Fast Grants ,

Enhanced SARS-CoV-2 neutralization by dimeric IgA

n 111) and contacts (
K and
L) The normalized AUC of anti-RBD IgA (K) or IgG (L) ELISA for patients with gastrointestinal (GI) symptoms (
n 32) and without GI symptoms (
n 117) was plotted. The
r and
P values for the correlations in (C) to (G) were determined by two-tailed Spearman’s correlations. For (H) to (L), horizontal bars indicate median values. Statistical significance was determined using a two-tailed Mann-Whitney
U test.
P 0.005) and severity of symptoms (
P 0.0001) but not timing of sample collection relative to onset (
P 0.69) or age (
P 0.22) (Fig. 1, C to F). Concentrations of anti-RBD IgA antibodies correlated strongly with anti-RBD IgG concentrations ( ....

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