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Selective Use of Neoadjuvant Chemoradiation Is a Viable Approach in Locally Advanced Rectal Cancer

Deb Schrag, MD, MPH, discusses the rationale for exploring the use of selective preoperative chemoradiation in patients with locally advanced rectal cancer, the safety and efficacy findings from the PROSPECT trial, and the importance of reviewing patient-reported outcomes during clinical trials. ....

New York , United States , Georgej Bosl , Deb Schrag , National Cancer Institute , Department Of Medicine , Memorial Sloan Kettering Cancer Center , Cancer Care , Common Terminology Criteria , Adverse Events , National Cancer , Locally Advanced Rectal Cancer , Rectal Cancer , Gi Cancer , Asco Annual Meeting ,

Presurgical FOLFOX/Chemo as Effective as Chemoradiation in Rectal Cancer

Patients with locally advanced rectal cancer treated with FOLFOX before surgery had similar outcomes and side effect profiles to those treated with presurgical pelvic chemoradiation. ....

New York , United States , Deb Schrag , Georgej Bosl , Pamelal Kunz , Department Of Medicine , Memorial Sloan Kettering Cancer Center , New England Journal , Rectal Cancer , Asco Annual Meeting ,