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Biomarker Found for Diagnosing Vascular Dementia

Biomarker Found for Diagnosing Vascular Dementia
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Inhibitory neuron dysfunction emerges as a modulable mechanism of hyperexcitability

A small group of brain cells linked in a circuit is responsible for setting off whole-brain seizures in a rare form of epilepsy affected by blood sugar levels, a study led by UT Southwestern researchers suggests. The finding, published in Science Translational Medicine, could lead to new treatments for other metabolic disorders in the brain, the authors said.

UTSW scientists identify brain circuit that triggers rare, blood sugar-dependent epilepsy

Positron emission tomography (PET) images of mouse brains in the study show decreased brain glucose with GLUT1 (G1D) deficiency relative to normal (control). The color scale at right indicates the amount of glucose present, increasing up the scale.

Gene Editing Therapy in Early Stages of Huntington s Disease May Slow Down Symptom Progression, Mouse Study Shows

Gene Editing Therapy in Early Stages of Huntington s Disease May Slow Down Symptom Progression, Mouse Study Shows
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Gene therapy in early stages of Huntington s disease may slow down symptom progression

Gene therapy in early stages of Huntington s disease may slow down symptom progression
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