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and Chair of the Steering Committee for SOS-AMI, commented: P2Y 12 receptor antagonists have been used in the treatment of millions of patients globally, and their safety and efficacy profiles are well established. Despite the success of chronic treatment with this class and other effective interventions, patients are still suffering recurrent heart attacks. The idea for patients to self-inject early in the onset of symptoms is truly innovative. The subcutaneous route of administration could overcome the onset delay observed with oral compounds from the same class. To be effective, any antithrombotic treatment for use at the onset of AMI symptoms should be rapidly absorbed and potent, acting quickly to inhibit thrombus formation at an early stage. Inhibition should be reversed after a few hours to avoid interfering with later patient management decisions. It must also have an appropriate safety profile for use prior to formal diagnosis of AMI. Selatogrel has the ....
“Think of inflammation as the body’s natural response to protect itself against harm. There are two types: acute and chronic. You’re probably more familiar with the acute type, which occurs when you bang your knee or cut your finger. Your immune system dispatches an army of white blood cells to surround and protect the area, creating visible redness and swelling. The process works similarly if you have an infection like the flu or pneumonia. So in these settings, inflammation is essential – without it, injuries could fester and simple infections could be deadly,” writes Dr Deepak Bhatt, the Editor in Chief of the ....
Article content Researchers from Switzerland and the U.S. write in the recent study that marijuana’s long-term effects on cardiovascular health are understudied. As such, they looked at data from the CARDIA (Coronary Artery Risk Development in Young Adults) Study, a cohort of 5,115 Black and white women and men at Year 20 visit. Specifically, they considered hardening of the arteries at mid-life and lifetime exposure to marijuana and tobacco smoking. “This study adds to the growing body of evidence that there might be no association between the average population level of marijuana use and subclinical atherosclerosis.” / Photo by Vadzim Kushniarou/Getty Images ....