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Invasive breast cancer and breast cancer death after non-screen detected ductal carcinoma in situ from 1990 to 2018 in England: population based cohort study

Objectives To evaluate the long term risks of invasive breast cancer and death related to breast cancer after non-screen detected ductal carcinoma in situ. Risks for women in the general population and for women diagnosed with ductal carcinoma in situ via the screening programme were compared.

Design Population based cohort study.

Setting Data from the National Disease Registration Service.

Participants All 27 543 women in England who were diagnosed with ductal carcinoma in situ, outside the NHS breast screening programme, during 1990 to 2018.

Main outcome measures Incident invasive breast cancer and death caused by breast cancer.

Results By 31 December 2018, 3651 women with non-screen detected ductal carcinoma in situ had developed invasive breast cancer, more than four times higher than expected from national cancer incidence rates (ratio of observed to expected rate was 4.21 (95% conference interval 4.07 to 4.35)). The ratio of observed to expect ....

United Kingdom , United States , David Dodwell , Hilary Stobart , Gurdeeps Mannu , Sarahc Darby , John Broggio , Mairead Mackenzie , University Of Oxford , Cancer Research United Kingdom , Digital Data Access Request Service , Cancer Research United Kingdom Clinician Scientist Fellowship , National Health Service , Research Ethics Committee , National Disease Registration Service , Public Health England , National Institute Of Clinical Excellence , Nuffield Department Of Population Health , National Disease Registration , Conclusions For , Regional Cancer Registries , Nuffield Department , Population Health , Humber Leeds East , College Station , Independent Cancer Patient Voice ,

Risk of breast cancer death after a diagnosis of early invasive breast cancer

Risk of breast cancer death after a diagnosis of early invasive breast cancer
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United Kingdom , Hilary Stobart , Carolyn Taylor , David Dodwell , Mairead Mackenzie , United Kingdom Medical Research Council , Cancer Research United Kingdom , University Of Oxford , National Institute , Health Research Oxford Biomedical Centre ,

Breast cancer mortality in 500 000 women with early invasive breast cancer in England, 1993-2015: population based observational cohort study

Breast cancer mortality in 500 000 women with early invasive breast cancer in England, 1993-2015: population based observational cohort study
bmj.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from bmj.com Daily Mail and Mail on Sunday newspapers.

United Kingdom , Amandaj Kerr , Carolyn Taylor , Paul Mcgale , David Dodwell , Timothy Whelan , John Broggio , Gurdeep Mannu , Sarahc Darby , Jake Probert , National Cancer Registration , University Of Oxford , Analysis Service , United Kingdom Medical Research Council , Cancer Research United Kingdom , Conclusions These , National Institute , Health Research Oxford Biomedical Centre , Open Access , Creative Commons Attribution ,

Stroke Incidence Trends Higher in Younger vs Older Adults

The substantial decrease in stroke incidence at older ages in high-income countries is not also occurring in younger adults and there s an urgent need to understand why, researchers say. ....

United States , United Kingdom , Peter Rothwell , Wolfson Foundation , Masonic Charitable Foundation , University Of Oxford , Wolfson Centre For Prevention Of Stroke , Wolfson Centre , Medscape Medical , National Institute , Health Research Oxford Biomedical Centre , Wellcome Trust , Erebrovascular Accident , Va Cerebrovascular Accident , Ischemic Stroke , Subarachnoid Hemorrhage , Ubarachnoid Bleeding , Leeding Subarachnoid , Traumatic Brain Injury , Bi Traumatic Brain Injury , Intracerebral Hemmorhage ,

Phase-Specific DBS Suppresses Postural and Kinetic Tremor

Phase-specific deep brain stimulation can relieve essential tremor across different contexts and motor states. ....

United Kingdom , Research Council United Kingdom , National Institute , Health Research Oxford Biomedical Centre , Medical Research Council , Deep Brain Stimulation , Bs Deep Brain Stimulation , Essential Tremor ,