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World Hepatitis Day | Hepatitis D Is Zoonotic & Came From America: New Study Dismantles Everything We Knew About The Disease

New study reveals that Hepatitis D is zoonotic and came from America. This finding could help explain the sudden outbreak of the disease globally.

Panama , Hepatitis , Hepatitis-d , New-study , World-hepatitis-day , Zoonotic , Virus ,

#VisualAbstract: A Phase 3, Randomized Trial of Bulevirtide in Chronic Hepatitis D

Click here to read this study in NEJM. ©2023 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute

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Buleviritide reduces viral load in patients with chronic hepatitis D

1. In this randomized controlled trial, 48 weeks of buleviritide treatment resulted in reduced hepatitis D ribonucleic acid (RNA) levels in patients with chronic hepatitis D. 2. The buleviritide group also had lower alanine transaminase (ALT) levels as compared to controls. Evidence Rating Level: 1 (Excellent) Study Rundown: Hepatitis D virus (HDV) is an RNA

Minute-medicine-inc , Rating-level , New-approaches , Chronic-hepatitis , Buleviritide , Chronic-disease , Hepatitis , Hepatitis-d , Hepatology , Immunology , Infectious-disease

Diagnosis of Viral Hepatitis Is Still a Major Challenge

World Hepatitis Day is an opportunity to remind people of the impact of viral hepatitis and to offer information that can help prevent, diagnose, and treat these diseases, said one expert.

Brazil , United-states , American , Brazilian , Julho-amarelo , World-health-organization , Brazilian-public-health-system , Health-education-challenging , National-immunization-program , Brazilian-ministry-of-health , American-health-organization , Paulo-society-of-infectious-diseases

Early Trial Results May Hold Promise for Patients With HDV

There is no approved treatment for chronic hepatitis D virus infection in the United States, but recent phase 3 trial results showed encouraging safety and efficacy associated with bulevirtide.

United-states , Americans , Marcg-ghany , European-medicines-agency , National-institute-of-diabetes , New-england-journal , National-institute , Drug-designation , Hdv , Hepatitis-d ,

Bulevirtide for Hep D: Phase 3 Data Now Published in NEJM

Bulevirtide, an investigational, first-in-class hepatitis delta virus entry-inhibitor, significantly reduced viral load and normalized liver enzymes in patients.

Hannover , Niedersachsen , Germany , Heiner-wedemeyer , Gilead-sciences , Drug-administration , Hannover-medical-school , New-england-journal , Biliary-disease , Allbladder-disease , Hepatitis-d , Hepatitis

Hepatitis D Virus-Like Agents Are Ubiquitous Throughout The Animal Kingdom

Contrary to previous assumptions, hepatitis D virus-like agents seem to be active in a range of different animal species, from fish all the way to termites.

United-kingdom , Melbourne , Victoria , Australia , China , Chinese , Scotland , Just-ducks , Hepatitis-d , Hepatitisd-virus , Hdv

FDA Rejects Bulevirtide for Hepatitis D

The FDA cited concerns over the production and delivery of bulevirtide, an investigational, first-in-class hepatitis delta virus entry-inhibitor that received conditional approved in Europe in 2020.

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Bulevirtide Reduces Hepatitis D Viral Load

Data from an ongoing study in patients with compensated cirrhosis and clinically significant portal hypertension have raised hope for an emerging treatment option in this rare, deadly disease.

Italy , Milan , Lombardia , United-states , France , Maggiore-policlinico , Bulevirtide-hepcludex , Marc-bourli , International-liver-congress , Elisabetta-degasperi , Grand-hospital-maggiore-policlinico , Unmet-therapeutic