Page 7 - Histamine News Today : Breaking News, Live Updates & Top Stories | Vimarsana

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Cluster headaches induced by pituitary adenylate cyclase-activating polypeptide-38 or vasoactive intestinal polypeptide do not alter CGRP levels, new research suggests.

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Background: There is currently no effective treatment for cognitive impairment associated with schizophrenia (CIAS). Recent studies have shown that increased histamine levels in the brain may help to improve CIAS symptoms. Betahistine is an H1-receptor agonist and H3-receptor antagonist. This study evaluated the effect of high-dose betahistine on cognitive function as well as its safety in Chinese Han patients with schizophrenia. Methods: This randomized double-blind, placebo-controlled trial enrolled 89 patients with schizophrenia who were randomly administered betahistine (72 mg/d) or placeb...

The draft Compliance Policy Guide CPG would revise two guidance levels for the presence of histamine in fish; elevated histamine levels can be prevented in fish by adherence to Current Good Manufacturing Practices and Hazard Analysis Critical Control Point HACCP principles.