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Clopidogrel superior to aspirin for long-term post-stent maintenance


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Clopidogrel outperformed aspirin in what is believed to be the first and largest randomized trial to compare the effectiveness of the two antiplatelet drugs as long-term maintenance therapy for patients who had no adverse events after one year of dual antiplatelet therapy (DAPT) following the insertion of a coronary stent. After two years of follow-up, chronic maintenance therapy with clopidogrel resulted in a 30% reduction in deaths, heart attacks, strokes or major bleeding events, according to research presented at the American College of Cardiology s 70th Annual Scientific Session.
These data confirm our working hypothesis that long-term maintenance antiplatelet monotherapy with clopidogrel produces better outcomes than aspirin in patients who are adverse event-free at one year after coronary stenting, said Hyo-Soo Kim, MD, PhD, professor of internal medicine at Seoul National University Hospital in South Korea and lead author of the study. ....

Soult Ukpyolsi , South Korea , Hyo Soo Kim , Nicole Napoli , Yann Nguyen , Antiplatelet Monotherapy , Seoul National University Hospital , American College Of Cardiology , Korean Ministry Of Health , American College , Annual Scientific , South Korean Ministry , Host Exam Randomized Controlled Trial , தெற்கு கொரியா , ஹயோ சூ கிம் , நிக்கோல் ந்யாபலீ , ஆண்டு ஂக்யந் , சியோல் தேசிய பல்கலைக்கழகம் மருத்துவமனை , அமெரிக்கன் கல்லூரி ஆஃப் இருதயவியல் , கொரியன் அமைச்சகம் ஆஃப் ஆரோக்கியம் , அமெரிக்கன் கல்லூரி , ஆண்டு அறிவியல் , தெற்கு கொரியன் அமைச்சகம் ,